发明名称 Test System for the Discovery of Substances for the Promotion of Neuraxonal Growth
摘要 The invention relates to a method for identifying or testing active substances, which influence the growth and survival of nerve cells, wherein a cell is brought into contact with at least one substance and subsequently, within said cell, the mRNA of the beta-actin or the beta-actin protein alone or together with the SMN protein and/or a ribonucleic protein hnRNP, in particular the ribonucleic protein hnRNP-R and/or hnRNP-Q, are determined, and the determined amounts of said components are compared to the amounts of said components in a cell, which has not been brought into contact with the prospective active substance, to a test system for carrying-out said method and to uses of such test systems.
申请公布号 US2008020964(A1) 申请公布日期 2008.01.24
申请号 US20040550385 申请日期 2004.03.16
申请人 SENDTNER MICHAEL;ROSSOLL WILFRIED;JABLONKA SIBYLLE 发明人 SENDTNER MICHAEL;ROSSOLL WILFRIED;JABLONKA SIBYLLE
分类号 A61K31/00;A61P25/00;C12Q1/02;C12Q1/68;G01N33/50;G01N33/68 主分类号 A61K31/00
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