发明名称 |
TETRAHYDROFURO [3, 2-B] PYRR0L-3-0NE INTERMEDIATES |
摘要 |
<p>The present invention relates to a process for preparing a compound of formula (Ia), (Ib), (Ic) or (Id), or a pharmaceutically acceptable salt, hydrate, solvate, complex or prodrug thereof, said process comprising the steps of: (A) (i) treating a compound of formula (IVa), where R<SUP>48</SUP> is alkyl or tosyl, with an oxidising agent to form a compound of formula (Va); and (ii) converting said compound of formula (Va) to a compound of formula (Ia) or (Ic); or (B) (i) treating a compound of formula (IVb), where R<SUP>48</SUP> is alkyl or tosyl, with an oxidising agent to form a compound of formula (Vb); and (ii) converting said compound of formula (Vb) to a compound of formula (Ib) or (Id).</p> |
申请公布号 |
WO2008007132(A1) |
申请公布日期 |
2008.01.17 |
申请号 |
WO2007GB02669 |
申请日期 |
2007.07.13 |
申请人 |
ARMURA THERAPEUTICS LIMITED;QUIBELL, MARTIN;NALLY, JAMES;PATIENT, LEE;WANG, YIKANG;DAGOSTIN, CLAUDIO;WATTS, JOHN, PAUL |
发明人 |
QUIBELL, MARTIN;NALLY, JAMES;PATIENT, LEE;WANG, YIKANG;DAGOSTIN, CLAUDIO;WATTS, JOHN, PAUL |
分类号 |
C07D307/28;C07D491/04;C07D493/04 |
主分类号 |
C07D307/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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