摘要 |
PROBLEM TO BE SOLVED: To provide a compound exhibiting HDS1-inhibiting actions or the like that is useful as a prophylactic or therapeutic agent for pathology in which a glucocorticoid participates, for example, metabolic diseases such as diabetes, insulin resistance, diabetic complications, obesity, hyperlipidemia, hypertension or fatty liver, or the like, and its applications. SOLUTION: The prophylactic or therapeutic agent for pathology in which a glucocorticoid participates or an 11βHSD1-inhibiting agent comprises a compound represented by general formula [1'] or a salt thereof. In the formula, the ring A, R<SP>2</SP>, R<SP>3</SP>, R<SP>4</SP>and X are each defined specifically. COPYRIGHT: (C)2008,JPO&INPIT
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