TARGETED DELETIONS USING RETROELEMENT-MEDIATED PLACEMENT OF RECOMBINATION SITES
摘要
The present invention provides methods, nucleic acid constructs, and kits for selectively deleting a region of a nucleic acid sequence. Specifically, it utilizes retargeting retroelements to place site-specific recombination sites at targeted locations in the nucleic acid sequence. The region between the recombination sites is then deleted using a site-specific recombination system.
申请公布号
WO2007117852(A3)
申请公布日期
2007.12.06
申请号
WO2007US64031
申请日期
2007.03.15
申请人
SIGMA-ALDRICH CO.;SPEARS, MELISSA;DAVIS, GREG;KAYSER, KEVIN