GELATIN NON-WOVEN STRUCTURES PRODUCED BY A NON-TOXIC DRY SOLVENT SPINNING PROCESS

摘要

The present application discloses an alternative method for the formation of non-woven with fibers in the 1 to 200µm range. Using an aqueous solution of gelatin (optionally with <30% of low molecular weight alcohol) the fibers are ejected utilizing pressurized air emitted from nozzle and the non-woven formed directly from the emitted thin fibers. The gelatin non-woven can be cross-linked by heat-treatment or chemical cross-linking, and the non-woven is biocompatible as measured by fibroblast growth in vitro and wound healing on pigs in vivo.