发明名称 |
INHIBITOR OF PROTEIN-AGGLOMERATED FIBROSIS ASSOCIATED WITH NEURODEGENERATIVE DISEASE |
摘要 |
PROBLEM TO BE SOLVED: To provide a composition for inhibiting fibrosis and agglomeration of proteins includingα-synuclein. SOLUTION: The composition is prepared by adding a component containing PQQ (pyrrolo-quinoline quinone) and a PQQ derivative to a solution containing proteins includingα-synuclein. The fibrosis and agglomeration of proteins are inhibited by using the composition. The composition enables the development of medicaments for disorders caused by protein degeneration including Parkinson's disease. COPYRIGHT: (C)2008,JPO&INPIT
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申请公布号 |
JP2007269769(A) |
申请公布日期 |
2007.10.18 |
申请号 |
JP20060235398 |
申请日期 |
2006.08.31 |
申请人 |
ULTIZYME INTERNATIONAL LTD;TOKYO UNIV OF AGRICULTURE & TECHNOLOGY |
发明人 |
HAYADE KOJI;IKEBUKURO KAZUNORI;HANAOKA SHINGO |
分类号 |
A61K31/4745;A61K31/198;A61K38/00;A61P25/16;A61P25/28;A61P43/00;C07D471/04;C07K14/47 |
主分类号 |
A61K31/4745 |
代理机构 |
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地址 |
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