发明名称 INHIBITOR OF PROTEIN-AGGLOMERATED FIBROSIS ASSOCIATED WITH NEURODEGENERATIVE DISEASE
摘要 PROBLEM TO BE SOLVED: To provide a composition for inhibiting fibrosis and agglomeration of proteins includingα-synuclein. SOLUTION: The composition is prepared by adding a component containing PQQ (pyrrolo-quinoline quinone) and a PQQ derivative to a solution containing proteins includingα-synuclein. The fibrosis and agglomeration of proteins are inhibited by using the composition. The composition enables the development of medicaments for disorders caused by protein degeneration including Parkinson's disease. COPYRIGHT: (C)2008,JPO&INPIT
申请公布号 JP2007269769(A) 申请公布日期 2007.10.18
申请号 JP20060235398 申请日期 2006.08.31
申请人 ULTIZYME INTERNATIONAL LTD;TOKYO UNIV OF AGRICULTURE & TECHNOLOGY 发明人 HAYADE KOJI;IKEBUKURO KAZUNORI;HANAOKA SHINGO
分类号 A61K31/4745;A61K31/198;A61K38/00;A61P25/16;A61P25/28;A61P43/00;C07D471/04;C07K14/47 主分类号 A61K31/4745
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