SUSTAINED RELEASE PHARMACEUTICAL COMPOSITION ON THE BASIS OFA RELEASE SYSTEM COMPRISING AN ACID-SOLUBLE POLYMER AND A PH-DEPENDENT POLYMER.

摘要

Sustained release pharmaceutical composition comprising at least one poorly soluble active agent(s), at least one solubilizer, a release rate controlling polymer system consisting of an acid-soluble polymer and a pH-dependent polymer, and optionally other pharmaceutically acceptable excipients. The present invention also describes a process for preparation of such compositions and method of using such compositions. The sustained release compositions are useful in providing therapeutically effective levels of active agent(s) for extended periods of time.