| 摘要 |
<p>A novel compound which is useful as a therapeutic or preventive agent for diseases attributable to gastric hydrochloric acid. It has excellent gastric hydrochloric acid secretion inhibitory activity and is richer in the retention of gastric hydrochloric acid secretion inhibitory activity. It can keep the gastric pH high for long. It is safer and has moderate physicochemical stability. It is a compound represented by the general formula (1) (wherein R<sup>1</sup> and R<sup>3</sup> are the same or different and each represents hydrogen or C<sub>1-6</sub> alkyl; R<sup>2</sup> represents (5,5-dimethyl-1,3-dioxan-2-yl)methoxy, 5,7-dioxaspiro[2.5]oct-6-ylmethoxy, 1,5,9-trioxaspiro[5.5]undec-3-ylmethoxy, (2,2-dimethyl-1,3-dioxan-5-yl)methoxy, etc.; R<sup>4</sup>, R<sup>5</sup>, R<sup>6</sup>, and R<sup>7</sup> each represents hydrogen, halogeno, C<sub>1-6</sub> alkyl, C<sub>1-6</sub> haloalkyl, C<sub>1-6</sub> alkoxy, C<sub>1-6</sub> haloalkoxy, etc.; and W<sup>1</sup> represents a single bond, methylene, or ethylene), a salt thereof, or a solvate of either.</p> |
