发明名称 |
PROTECTION PROBES |
摘要 |
The present invention features compositions and methods that are useful for storing labeled detection probes and detecting whether a target nucleic acid sequence is present in a sample. Preferred compositions are made up of a detection probe containing a label susceptible to a chemical or enzymatic alteration and a protection probe that protects the label from alteration and/or decreases the ability of the detection probe to inhibit nucleic acid amplification. Such compositions can be used, for example, to stabilize a detection probe label and to prevent a detection probe from hybridizing prematurely to amplified or target nuclei c acid.
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申请公布号 |
CA2362545(C) |
申请公布日期 |
2007.09.25 |
申请号 |
CA20002362545 |
申请日期 |
2000.02.11 |
申请人 |
GEN-PROBE INCORPORATED |
发明人 |
BRENTANO, STEVEN T.;NELSON, NORMAN C.;MCDONOUGH, SHERROL H. |
分类号 |
C12Q1/68;G01N33/483;C07H21/04;C12N15/09;G01N21/78;G01N33/53;G01N33/566;G01N33/58 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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