6-ALKENYL-, 6-ALKYNYL- AND 6-EPOXY-EPOTHILONE DERIVATIVE, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATION TO PHARMACEUTICAL PREPARATION

摘要

PROBLEM TO BE SOLVED: To provide a new 6-epoxy-epothilone, a method for producing the same, and a pharmaceutical preparation. SOLUTION: The 6-alkenyl-, 6-alkynyl- and 6-epoxy-epothilone derivatives are expressed by formula I. The method for producing thereof and application thereof to pharmaceutical preparations are provided. COPYRIGHT: (C)2007,JPO&INPIT