| 发明名称 |
REVERSE-TURN MIMETICS AS alpha 4ß INTEGRIN INHIBITORS |
| 摘要 |
<p>Conformationally constrained compounds which mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins are disclosed. Such reverse-turn mimetics have utility in the treatment of cell adhesion-indicated diseases, such as multiple sclerosis, atherosclerosis, asthma and inflammatory bowel disease.</p> |
| 申请公布号 |
EP1227813(B1) |
申请公布日期 |
2007.08.22 |
| 申请号 |
EP20000941610 |
申请日期 |
2000.06.20 |
| 申请人 |
MYRIAD GENETICS, INC. |
发明人 |
KAHN, MICHAEL;EGUCHI, MASAKATSU;KIM, HWA-OK;STASIAK, MARCIN |
| 分类号 |
A61K31/4985;A61K31/517;A61K31/519;A61K31/551;A61K38/00;A61P1/00;A61P3/10;A61P9/00;A61P9/08;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P17/00;A61P17/06;A61P19/02;A61P25/00;A61P25/28;A61P27/02;A61P29/00;A61P31/18;A61P35/00;A61P37/08;A61P43/00;C07B61/00;C07D487/04;C07D498/04;C07K5/02;C07K5/078 |
主分类号 |
A61K31/4985 |
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