| 发明名称 |
DELIVERY OF OPIOIDS THROUGH AN INHALATION ROUTE |
| 摘要 |
The present invention relates to the delivery of opioids through an inhalation route. Specifically, it relates to aerosols containing opioids that are used in inhalation therapy. In a method aspect of the present invention, an opioid is delivered to a patient through an inhalation route. The method comprises: a) heating a thin layer of an opioid, on a solid support, to form a vapor; and, b) passing air through the heated vapor to produce aerosol particles having less than 5% opioid degradation products. In a kit aspect of the present invention, a kit for delivering an opioid through an inhalation route is provided which comprises: a) a thin layer of an opioid and b) a device for dispensing said thin layer as a condensation aerosol.
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| 申请公布号 |
US2007178052(A1) |
申请公布日期 |
2007.08.02 |
| 申请号 |
US20070621397 |
申请日期 |
2007.01.09 |
| 申请人 |
ALEXZA PHARMACEUTICALS, INC. |
发明人 |
RABINOWITZ JOSHUA D.;ZAFFARONI ALEJANDRO C. |
| 分类号 |
A61K9/12;A61K31/485;A61K9/00;A61K9/14;A61K9/72;A61K31/00;A61K31/13;A61K31/137;A61K31/138;A61K31/165;A61K31/167;A61K31/19;A61K31/192;A61K31/216;A61K31/27;A61K31/40;A61K31/403;A61K31/404;A61K31/4045;A61K31/405;A61K31/407;A61K31/4196;A61K31/421;A61K31/422;A61K31/423;A61K31/437;A61K31/439;A61K31/4402;A61K31/4418;A61K31/4525;A61K31/4545;A61K31/46;A61K31/473;A61K31/48;A61K31/49;A61K31/495;A61K31/496;A61K31/4985;A61K31/501;A61K31/505;A61K31/519;A61K31/53;A61K31/5415;A61K31/55;A61K31/551;A61K31/5513;A61K31/5517;A61K45/00;A61K47/48;A61M11/00;A61P15/10;A61P21/02;A61P25/06;A61P25/08;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/32;A61P29/00;A61P31/04;A61P37/08;A61P43/00;C07D471/04;C07D487/04;F24J1/00 |
主分类号 |
A61K9/12 |
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