Carboxylic acid compounds

摘要

The present invention relates to a carboxylic acid compound of formula (I): wherein R¹ is H, alkyl; m is 2, 3; n is 0-2; R² is phenyl, naphthyl, benzofuran, benzothiophene; Q is -CH₂-O-Cyc1, -CH₂-Cyc2, -L-Cyc3; R^3a and R^3b each independently is hydrogen, alkyl or taken together form tetrahydro-2H-pyran; a pharmaceutically acceptable salt thereof, a method for producing a process of the preparation thereof and a pharmaceutical agent comprising the same as an active ingredient. The compound of formula (I) have an antagonizing activity against PGE₂ receptor, specifically EP₃ receptor which is subtype thereof, and are useful for the prevention and/or treatment of itching, pain, urinary disturbance or stress disease.