NOVEL LIPID BASED CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS
摘要
<p>Novel controlled release pharmaceutical compositions are provided which release the active agent(s) over an extended period of time comprising a core wherein the said core comprises at least one active agent(s) which is preferably water soluble, a lipid system comprising at least one lipid component(s), at least one water insoluble release modifier(s), at least one channel forming agent(s) and optionally one or more pharmaceutically acceptable excipients; and at least one coat. Preferably the coating composition comprises at least one hydrophilic pH independent polymer(s) and optionally one or more pharmaceutically acceptable excipients. Also provided is a process of preparation of such compositions and method of using them.</p>