发明名称 |
Piperidine derivatives and methods of use |
摘要 |
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally monocyclic and bicyclic compounds and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.
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申请公布号 |
US2007093467(A1) |
申请公布日期 |
2007.04.26 |
申请号 |
US20060580202 |
申请日期 |
2006.10.11 |
申请人 |
CHEMOCENTRYX, INC. |
发明人 |
ZHANG PENGLIE;PENNELL ANDREW M.;CHEN WEI;GREENMAN KEVIN L.;SULLIVAN EDWARD J.;LI LIANFA |
分类号 |
A61K31/55;A61K31/454;A61K31/496;A61K31/5377;A61K31/541;C07D401/02;C07D403/02;C07D413/02;C07D417/02 |
主分类号 |
A61K31/55 |
代理机构 |
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代理人 |
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地址 |
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