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发明名称 IRAKS AS MODIFIERS OF BRANCHING MORPHOGENESIS AND METHODS OF USE
摘要 Human IRAK genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for identifying modulators of branching morphogenesis, comprising screening for agents that modulate the activity of IRAK are provided.
申请公布号 WO2005051314(A3) 申请公布日期 2007.04.26
申请号 WO2004US39408 申请日期 2004.11.23
申请人 EXELIXIS, INC.;TROWE, TORSTEN;VOGEL, ANDREAS MICHAEL;JIN, YISHENG;SCHEEL, JOCHEN KONRAD;ODENTHAL, JORG HEINRICH;WILL, TORSTEN TILMANN;BJERKE, LYNN MARGARET;HEUER, TIMOTHY S.;HABECK, HINRICH ALEXANDER;KARIM, FELIX D.;KOBLIZEK, THOMAS I.;LANGHEINRICH, ULRIKE;PLOWMAN, GREGORY D.;SCHULTE-MERKER, STEFAN;STOTT, GORDON MARK;SWIMMER, CANDACE 发明人 HABECK, HINRICH ALEXANDER;KARIM, FELIX D.;KOBLIZEK, THOMAS I.;LANGHEINRICH, ULRIKE;PLOWMAN, GREGORY D.;SCHULTE-MERKER, STEFAN;STOTT, GORDON MARK;SWIMMER, CANDACE
分类号 C12Q1/68;A61K;C12N;C12N9/12;C12Q1/48;G01N33/50;G01N33/53;G01N33/574 主分类号 C12Q1/68
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