摘要 |
The inventions provide an isolated antiviral peptide characterized by the amino acid sequence GDEPLENYLDTEYF (SEQ ID:NO 1) and a significant in vitro binding affinity for HIV-1 gp 120 and gp 41 and human CD4 cells. It has postulated anti-retroviral activity in vivo, particularly anti-HIV-1 activity. The inventions further provide pharmaceutical compositions comprising this peptide and methods for preventing, treating, and diagnosing HIV-1 infections and HIV-1 related conditions such as AIDS and ARC with these compositions. |