摘要 |
PROBLEM TO BE SOLVED: To provide a method for producing a 3-substituted aminocyclic amine derivative in a high yield/high purity safely and inexpensively. SOLUTION: This method for producing the cyclic amine derivative is provided by treating a compound expressed by formula (1) [wherein, (m) is 1, 2, 3 or 4; R<SP>1</SP>, R<SP>3</SP>are each independently H or the like; Ar is a substitutable aryl; R<SP>2</SP>s do not exist or exist by 1 or 2 and are each independently a halogen atom or the like; R<SP>4</SP>, R<SP>5</SP>are each independently H or a substitutable alkyl] with a borane-based reducing agent. COPYRIGHT: (C)2007,JPO&INPIT
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