Prolyl endopeptidease (PEP) and glutamine endoprotease for the treatment of Celiac Sprue
摘要
Administering an effective dose of glutenase to a Celiac or dermatitis herpetiformis patient reduces levels of toxic gluten oligopeptides, thereby attenuating or eliminating the damaging effects of gluten.
申请公布号
EP1740197(A1)
申请公布日期
2007.01.10
申请号
EP20050714080
申请日期
2005.02.23
申请人
ALVINE PHARMACEUTICALS, INC.;THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
发明人
SHAN, LU;BETHUNE, MICHAEL;KHOSLA, CHAITAN;GASS, JONATHAN