摘要 |
Heterocyclic-substituted tricyclics of the formula (I) or a pharmaceutically acceptable salt or solvate of said compound, isomer or racemic mixture wherein ---- represents an optional double bond, the dotted line is optionally a bond or no bond, resulting in a double bond or a single bond, as permitted by the valency requirement and wherein A, B, G, M, X, J, n, Het, R<SUP>3</SUP>, R<SUP>10</SUP>, R<SUP>11</SUP>, R<SUP>32</SUP> and R<SUP>33</SUP> are herein defined and the remaining substituents are as defined in the specification, are disclosed, as well as pharmaceutical compositions containing them and a method of treating diseases associated with thrombosis, atherosclerosis, restenosis, hypertension, angina pectoris, arrhythmia, heart failure, and cancer by administering said compounds. Combination therapy with other cardiovascular agents is also claimed. |
申请人 |
SCHERING CORPORATION;CHACKALAMANNIL, SAMUEL;CHELLIAH, MARIAPPAN, V.;XIA, YAN;EAGEN, KEITH, A. |
发明人 |
CHACKALAMANNIL, SAMUEL;CHELLIAH, MARIAPPAN, V.;XIA, YAN;EAGEN, KEITH, A. |