发明名称 RIBONUCLEIC ACID COMPOUND AND METHOD OF LIQUID-PHASE SYNTHESIS OF OLIGONUCLEIC ACID COMPOUND
摘要 <p>A novel ribonucleic acid compound in a phosphoric triester form. It is important for the liquid-phase synthesis of an oligo RNA. It is a ribonucleic acid compound represented by the following general formula. In the formula, B represents adenine, guanine, cytosine, uracil, or a modification of any of these; R21 represents optionally substituted aryl or optionally substituted, mono- or bicyclic, heterocyclic group; R20 represents hydrogen or optionally substituted alkyl; and R1 represents a protective group at least 90% of which can be eliminated in 24 hours at any temperature in the range of 0 to 60°C under acid conditions of a pH of 2 to 4.</p>
申请公布号 KR20060129026(A) 申请公布日期 2006.12.14
申请号 KR20067016888 申请日期 2006.08.23
申请人 NIPPON SHINYAKU CO., LTD. 发明人 OHGI TADAAKI;UEDA TOSHIHIRO;MARUYAMA YASUFUMI;MASUDA HIROFUMI
分类号 C07H19/10;A61K31/7068;A61K31/7072;A61K31/7076;A61K31/7088;C07H19/067;C07H19/167;C07H19/20;C07H21/02;C07H21/04 主分类号 C07H19/10
代理机构 代理人
主权项
地址