发明名称 PLATELET ADP REZEPTOR INHIBITOREN
摘要 Novel compound of formulae (I), which more particularly, include sulfonylurea derivatives, sulfonylthiourea derivatives, sulfonylguanidine derivatives, sulfonylcyanoguanidine derivatives, thioacylsulfonamide derivatives, and acylsulfonamide derivatives which are effective platelet ADP receptor inhibitors. These derivatives may be used in various pharmaceutical compositions, and are particularly effective for the prevention and/or treatment of cardiovascular diseases, particularly those diseases related to thrombosis. The invention also relates to the use of an effective amount of a compound of formulae (I), or a pharmaceutically acceptable salt thereof, in the manufacture of a pharmaceutical composition for preventing or treating thrombosis in a mammal.
申请公布号 DE60214730(D1) 申请公布日期 2006.10.26
申请号 DE2002614730 申请日期 2002.07.25
申请人 PORTOLA PHARMACEUTICALS INC. 发明人 SCARBOROUGH, M.;JANTZEN, HANS-MICHAEL;HUANG, WOLIN;SEDLOCK, M.;MARLOWE, K.;KANE-MAGUIRE, A.
分类号 C07D239/96;C07D521/00;A61K31/16;A61K31/175;A61K31/381;A61K31/4035;A61K31/4196;A61K31/4725;A61K31/519;A61K31/54;A61K31/64;A61P7/02;A61P9/00;A61P9/04;A61P9/10;A61P9/14;A61P43/00;C07D209/48;C07D213/70;C07D239/22;C07D239/50;C07D333/34;C07D401/04;C07D401/12;C07D405/12;C07D409/12;C07D409/14;C07D417/12;C07D487/04;C07D495/04 主分类号 C07D239/96
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