| 摘要 |
Disclosed herein is a use of one or more active agent selected from: the steroidal sapogenins, related compounds of formula (I) and formula (Ia) (wherein the variables are as defined in the specification), all their stereoisomers, unless stereochemically defined above, and racemic mixtures, all their pharmaceutically acceptable salts, and all mixtures and combinations thereof in the manufacture of a medicament for the treatment or prevention of, (i) non-cognitive neurodegeneration, (ii) non-cognitive neuromuscular degeneration, (iii) motor-sensory neurodegeneration, or (iv) receptor dysfunction or loss in the absence of cognitive, neural and neuromuscular impairment, in an animal suffering therefrom or susceptible thereto and in which symptoms of cognitive dysfunction are absent.
|
