2-AMINO-4-ACETYL-7-BROMO-8-HYDROXY-3,8-DIHYDROTHIAZOLO[5,4-b]INDOLE HYDROBROMIDE PROTECTING BODY AGAINST HYPOXIA AND LIVER AGAINST POISONING WITH CARBON TETRACHLORIDE

摘要

FIELD: organic chemistry, chemical technology, medicine. ^ SUBSTANCE: invention relates to a new 2-amino-4-acetyl-7-bromo-8b-hydroxy-3a,8b-dihydrothiazolo[5,4-b]indole hydrobromide of the formula (1) that is able to protect body against hypoxia and liver against poisoning with carbon tetrachloride. The melting point of this compound is 266-267°C (with decomposition). The compound is synthesized from 1-acetyl-5-bromo-3-indolinone and elemental bromine in dioxane medium followed by addition of thiourea in isopropyl alcohol. ^ EFFECT: valuable medicinal properties of compound. ^ 2 tbl, 1 ex