发明名称 |
Method for the crystallization of human serum albumin |
摘要 |
The present invention relates to the purification and production of human albumin from various sources through crystallization and repeated crystallization. Basic features of the invented process include providing specific reaction conditions and precipitating reagents to maximize albumin crystallization. Solubility diagrams are utilized as the basis for process control of the invented method. The current invention specifically controls phosphate concentration, pH and temperature to precisely guide crystallization kinetics and crystal yield.
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申请公布号 |
US2006178309(A1) |
申请公布日期 |
2006.08.10 |
申请号 |
US20060378727 |
申请日期 |
2006.03.17 |
申请人 |
GTC-BIOTHERAPEUTICS, INC. |
发明人 |
VISURI KALEVI;UOTILA SINIKKA;FULTON SCOTT P.;COUTO DANIEL E. |
分类号 |
A61K38/38;C07K14/765 |
主分类号 |
A61K38/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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