发明名称 Tetracylic immunomodulatory compounds
摘要 The present invention relates to novel heterocyclic compounds, to methods for their preparation, to compositions containing them, and to methods and use for clinical treatment of medical conditions which may benefit from immunomodulation, including rheumatoid arthritis, multiple sclerosis, diabetes, asthma, transplantation, systemic lupus erythematosis and psoriasis. More particularly, the present invention relates to novel heterocyclic compounds, which are CD80 antagonists capable of inhibiting the interactions between CD80 and CD28.
申请公布号 US2006035919(A1) 申请公布日期 2006.02.16
申请号 US20050537538 申请日期 2005.09.15
申请人 MATTHEWS LAN R;HUXLEY PHILIP;MAGARACI FILIPPO;BRENNAN CHRIS J;UDDIN MUHAMMED K;PETTERSSON LARS O G;THRIGE DORTHE D G 发明人 MATTHEWS LAN R.;HUXLEY PHILIP;MAGARACI FILIPPO;BRENNAN CHRIS J.;UDDIN MUHAMMED K.;PETTERSSON LARS O.G.;THRIGE DORTHE D.G.
分类号 A61K31/4745;A61K31/4162;A61P37/02;C07D471/02;C07D471/04;C07D491/02 主分类号 A61K31/4745
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