发明名称 1,3-DIHYDROIMIDAZOLE FUSED-RING COMPOUND
摘要 The objective of this invention is to provide novel compounds that show excellent DPPIV-inhibiting activity. The present invention provides compounds represented by the general formula (I), salts thereof, or hydrates thereof, <CHEM> Äwherein, T<1> stands for a monocyclic or bicyclic 4 to 12-membered heterocycle having 1 or 2 nitrogen atoms in the ring, which may have substituents; in formula (I), the following formula <CHEM> represents a double bond or a single bond; X<3> denotes an oxygen atom or a sulfur atom; X<1> denotes a C2-6 alkynyl group which may have substituents; Z<1> denotes a nitrogen atom or the formula -CR<3>=; Z<2> and Z<3> each independently denote a nitrogen atom, the formula -CR<1>=, a carbonyl group, or the formula -NR<2>-; R<1>, R<2>, R<3>, and X<2> each independently denote a C1-6 alkyl group which may have substituents, and suchÜ.
申请公布号 PL377187(A1) 申请公布日期 2006.01.23
申请号 PL20030377187 申请日期 2003.12.02
申请人 EISAI R & D MANAGEMENT, CO., LTD. 发明人 KIRA KAZUNOBU;CLARK RICHARD;YOSHIKAWA SEIJI;UEHARA TAISUKE
分类号 C07D471/04;A61K31/522;A61P1/00;A61P3/04;A61P3/06;A61P3/10;A61P5/00;A61P9/00;A61P15/08;A61P19/10;A61P25/00;A61P29/00;A61P31/18;A61P35/00;A61P37/02;A61P37/08;A61P43/00;C07D473/16;C07D473/18;C07D473/24;C07D473/32;C07D473/40;C07D487/04 主分类号 C07D471/04
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