发明名称 |
METHOD FOR INTRODUCING DRUG AND APPARATUS FOR INTRODUCING DRUG |
摘要 |
PROBLEM TO BE SOLVED: To provide a method for introducing a drug by which the drug can selectively be introduced into a specific cell with an inexpensive apparatus and to provide the apparatus for introducing the drug. SOLUTION: The drug such as a therapeutic gene is injected into a biological tissue with a syringe to localize the drug near the cell into which the drug is to be introduced. A pigment (e.g. hemoglobin) as a target near the cell is irradiated with laser beams at≥100 ps pulse width to thereby introduce the drug into the cell. The laser pulse is selectively absorbed with the pigment (linear absorption) to induce a temperature rise and a pressure wave (a thermoelastic wave). Thereby, permeability into the cell membrane is increased. COPYRIGHT: (C)2006,JPO&NCIPI
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申请公布号 |
JP2005330194(A) |
申请公布日期 |
2005.12.02 |
申请号 |
JP20040147971 |
申请日期 |
2004.05.18 |
申请人 |
KEIO GIJUKU |
发明人 |
OBARA MINORU;OGURA MAKOTO;TERAKAWA MITSUHIRO;SATO SHUNICHI |
分类号 |
C12N15/09;A61K48/00;A61P43/00;C12M1/00;C12N13/00;(IPC1-7):A61K48/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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