Method for producing non-human mammal RNAi phenotype using papilloma virus vector

摘要

It is an object of the present invention to improve a method for introducing dsRNA, so as to improve the efficiency of obtaining mammals such as mice having an RNAi phenotype. The present invention provides a method for producing a non-human mammal wherein the function of a target gene is suppressed, which comprises introducing into cells a papilloma virus vector into which the target gene has been incorporated.