PROCESS FOR THE PREPARATION OF MAGNESIUM SALT OF OMEPRAZOLE

摘要

The present invention relates to a novel process for the preparation of magnesium salt of omeprazole which is used as active ingredient in pharmaceutical industry. The process discloses direct treatment of omeprazole with magnesium hydroxide that is a weak inorganic base as magnesium source. By this invention, the difficulties caused by magnesium hydroxide that is formed during omeprazole magnesium salt preparation can be eliminated and omeprazole magnesium can be obtained with high yield and high purity.