Multiple virus reaction assay

摘要

A method of assay for the outcome of a reaction comprises conducting a reaction between a first reactant and a second reactant to produce from the first reactant a product having at least one new structural feature not present in the first reactant or the second reactant, e.g. by cleaving the first reactant or adding to it, producing a multiple-phage tagged complex comprising at least two different viruses and said product or said first reactant, in which complex at least one of said viruses is connected to said product using a said new structural feature or is lost from said first reactant upon formation of said new structural feature, and determining the presence or amount of said complex by a dual-phage assay.