| 发明名称 |
THIAZOLYL UREA COMPOUNDS FOR THE TREATMENT OF CANCER |
| 摘要 |
Selected novel urea compounds are effective for prophylaxis and treatment of diseases, such as cell proliferation or apoptosis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving stoke, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes. |
| 申请公布号 |
PL372211(A1) |
申请公布日期 |
2005.07.11 |
| 申请号 |
PL20030372211 |
申请日期 |
2003.02.13 |
| 申请人 |
AMGEN INC. |
发明人 |
SANTORA VINCENT;ASKEW BENNY C.;DE MORIN FRENEL F.;HAGUE ANDREW;LABER ELLEN;LI AIWEN;LIU GANG;LOPEZ PATRICIA;NOMAK RANA;TEGLEY CHRISTOPHER;YANG KEVIN |
| 分类号 |
C07D491/113;A61K31/4439;A61K31/444;A61K31/4545;A61K31/4709;A61K31/4725;A61K31/496;A61K31/5377;A61K31/55;A61P1/04;A61P3/10;A61P7/00;A61P9/00;A61P9/10;A61P13/08;A61P13/12;A61P17/02;A61P17/06;A61P19/02;A61P25/00;A61P25/14;A61P25/16;A61P25/28;A61P27/02;A61P27/16;A61P29/00;A61P35/00;A61P43/00;C07D213/75;C07D277/48;C07D417/04;C07D417/12;C07D417/14;C07D453/02;C07D453/06;C07D471/04;C07D491/10;C07D521/00 |
主分类号 |
C07D491/113 |
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