发明名称 |
RECOMBINATION OF NUCLEIC ACID LIBRARY MEMBERS |
摘要 |
The invention provides, inter alia, a method of preparing a nucleic acid sequence that encodes a polypeptide that is displayed on a heterologous cell surface. The generally includes recombining a donor nucleic acid and an acceptor nucleic acid to form a recombined nucleic acid that encodes a polypeptide that is displayed. The recombination reaction is typically an in vivo reaction, in that at least the resolution of recombination intermediates occurs within a cell. Both site-specific recombination and homologous recombination can be used.
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申请公布号 |
WO03106639(A8) |
申请公布日期 |
2005.06.23 |
申请号 |
WO2003US18817 |
申请日期 |
2003.06.16 |
申请人 |
DYAX CORPORATION;HUFTON, SIMON, E. |
发明人 |
HUFTON, SIMON, E. |
分类号 |
C07K16/00;C12N15/10;C12N15/81;C40B40/02;G01N33/68;(IPC1-7):C12N15/74 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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