发明名称 |
MODIFIED MACROMOLECULES AND METHODS OF MAKING AND USING THEREOF |
摘要 |
Described herein are compounds such as macromolecules that have been modified in order to facilitate crosslinking by introduction of at least one hydrazide-reactive group and /or aminooxy-reactive group, and methods of making and using thereof for scar-free wound healing, for delivering bioactive agents or living cells, for preventing adhesion after a surgical procedure or for bone and cartilage repair. The macromolecule can be an oligonucleotide, a necleic acid, a polypeptide, a lipid, a glycoprotein, a glycolipid, a polysaccharide, a protein or a synthetic polymer, preferably a glycosaminoglycan like hyaluronan. |
申请公布号 |
WO2005056608(A1) |
申请公布日期 |
2005.06.23 |
申请号 |
WO2004US40726 |
申请日期 |
2004.12.06 |
申请人 |
UNIVERSITY OF UTAH RESEARCH FOUNDATION;PRESTWICH, GLENN, D.;SHU, XIAO, ZHENG;LIU, YANCHUN |
发明人 |
PRESTWICH, GLENN, D.;SHU, XIAO, ZHENG;LIU, YANCHUN |
分类号 |
A61L27/20;C08B37/00;C08B37/08;C08B37/10;C08H1/06;C08J3/075;C08L5/08;C12N5/00 |
主分类号 |
A61L27/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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