发明名称 Cloning and recombinant production of Polistinae venom enzymes such as hyaluronidase, and immunological therapies based thereon
摘要 <p>A unique clone of a Polistinae venom enzyme, recombinantly produced Polistinae venom enzymes, and methods of using the recombinant enzymes are provided. In a specific example, both phospholipase and hyaluronidase cDNA from Polistes annulares contain apparent "intronic" sequences. In still a further enbodiment, genetic engineering permits the construction of the "intronic" sequences to yield a useful coding sequence for expression of mature Polistinae venom enzyme proteins.</p>
申请公布号 EP1528102(A2) 申请公布日期 2005.05.04
申请号 EP20050001983 申请日期 1999.10.01
申请人 ROCKEFELLER UNIVERSITY 发明人 KING, TE, PAIO
分类号 C12N15/09;A61K38/46;A61K39/00;A61K48/00;A61P31/12;A61P31/18;A61P37/06;A61P37/08;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/16;C12N9/18;C12N9/20;C12N9/26;(IPC1-7):C12N9/18;C12N15/10;C12N15/54;A61K39/35 主分类号 C12N15/09
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