发明名称 |
HEPATITIS A, B-COMBINED VACCINE AND ITS LYOPHILIZED PREPARATION |
摘要 |
<p>The present invention relates to a hepatitis A, B-combined vaccine and its lyophilized preparation and, particularly to a hepatitis A, B-combined vaccine comprising a properly attenuated live hepatitis A virus and a purified hepatitis B surface antigen produced by a recombinant Chinese Hamster Ovary (CHO) cell and/or recombinant yeast, as well as its lyophilized preparation. The protectant used in the said preparation contains trehalose, glutamic acid, ascorbic acid, urea, sorbitol, inositol and dextran. The inflammation associated with hepatitis A virus and with hepatitis B virus can be prevented simultaneously by use of the hepatitis A, B-combined vaccine of the present invention.</p> |
申请公布号 |
WO2005037310(A1) |
申请公布日期 |
2005.04.28 |
申请号 |
WO2004CN00874 |
申请日期 |
2004.07.28 |
申请人 |
CHANGCHUN INSTITUTE OF BIOLOGICAL PRODUCTS;WANG, PENGFU;LIU, JINGYE;GUAN, GUIFAN;XIE, BAOSHENG;LUO, XUAN;LIU, LINGJIU;CHEN, WANGE |
发明人 |
WANG, PENGFU;LIU, JINGYE;GUAN, GUIFAN;XIE, BAOSHENG;LUO, XUAN;LIU, LINGJIU;CHEN, WANGE |
分类号 |
A61K39/29;(IPC1-7):A61K39/29;A61P31/12 |
主分类号 |
A61K39/29 |
代理机构 |
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代理人 |
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主权项 |
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