发明名称 Tricyclic inhibitors of poly(ADP-ribose) polymerases
摘要 Compounds of the formula below are poly(ADP-ribosyl)transferase (PARP) inhibitors, and are useful as therapeutics in treatment of cancers and the amelioration of the effects of stroke, head trauma, and neurodegenerative disease. As cancer therapeutics, the compounds of the invention may be used, e.g., in combination with cytotoxic agents and/or radiation.
申请公布号 US2005085460(A1) 申请公布日期 2005.04.21
申请号 US20040004261 申请日期 2004.12.03
申请人 发明人 WEBBER STEPHEN E.;CANAN-KOCH STACIE S.;TIKHE JAYASHREE;THORESEN LARS H.
分类号 A61K;A61K31/437;A61K31/4375;A61K31/55;A61K31/551;A61P;A61P3/10;A61P9/10;A61P25/28;A61P29/00;A61P35/00;A61P43/00;C07D;C07D209/00;C07D221/00;C07D223/00;C07D243/00;C07D471/06;C07D487/00;C07D487/06;C07D519/00;(IPC1-7):A61K31/55;A61K31/474;C07D471/02 主分类号 A61K
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