Method for diagnosing and treating predisposition for accelerated autosomal dominant polycystic kidney disease

摘要

A method for diagnosing a predisposition for accelerated autosomal dominant polycystic kidney disease (ADPKD) in a human male subject by detecting the Glu 298 Asp polymorphism of the ENOS gene is described. A diagnostic kit for detecting predisposition for accelerated ADPKD in a human subject is also disclosed. In addition, a method for treating a human subject predisposed to develop accelerated APDKD using NO-enhancing compounds is provided.