发明名称 METABOLISM AND EXCRETION PROMOTER FOR ORGANOHALOGEN-BASED COMPOUND
摘要 PROBLEM TO BE SOLVED: To provide a metabolism and excretion promoter capable of promptly promoting in a short period the metabolism and excretion of organohalogen-based compounds accumulated on biological tissues including liver and fat tissue. SOLUTION: The metabolism and excretion promoter for organohalogen-based compounds is a pharmaceutical preparation containing as the active ingredient a compound having thyroid hormone-like activity such as a thyroid hormone like 3,5,3'-triiodothyroxine(T3) or thyroxine(T4) or thyroid-stimulating hormone(TSH). This pharmaceutical preparation enables promoting in a short period of the metabolism and secretion of organohalogen-based compounds such as dioxins accumulated in human body, efficiently and promptly promoting the metabolism in the liver and secretion to urine of 2,3,7,8-tetrachlorodibenzo-p-dioxin(TCDD) having the highest toxicity among dioxins among others. COPYRIGHT: (C)2005,JPO&NCIPI
申请公布号 JP2005075768(A) 申请公布日期 2005.03.24
申请号 JP20030307614 申请日期 2003.08.29
申请人 JAPAN SCIENCE & TECHNOLOGY AGENCY 发明人 NAKANISHI TAKESHI;TANAKA KEIICHI
分类号 C07D319/24;A61K31/198;A61K38/22;A61P39/02;(IPC1-7):A61K31/198 主分类号 C07D319/24
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