发明名称 |
ПОЛУЧЕНИЕ КОМПОЗИЦИИ, СОДЕРЖАЩЕЙ НЕСТАБИЛЬНОЕ ПО ОТНОШЕНИЮ К КИСЛОТЕ ФИЗИОЛОГИЧЕСКИ АКТИВНОЕ СОЕДИНЕНИЕ, И СПОСОБ ЕЕ ПРОИЗВОДСТВА |
摘要 |
It is intended to disclose preparation composition which enable convenient production of sustained-release preparation composition containing acid-unstable physiologically active compound and have the desired sustained-release properties. Namely, preparation composition comprising a core containing an acid-unstable physiologically active compound and a coating with which the core is coated and which contains a mixture of a water-insoluble polymer and an enteric polymer. The preparation composition according to the present invention makes it possible to maintain an effective concentration in blood of the physiologically active compound over a long time, thereby improving its therapeutic effect. Moreover, the composition according to the present invention remains stable over prolonged storage. <IMAGE> |
申请公布号 |
RU2004118495(A) |
申请公布日期 |
2005.03.20 |
申请号 |
RU20040118495 |
申请日期 |
2002.11.20 |
申请人 |
ЭЙСАЙ КО., ЛТД. (JP) |
发明人 |
АОКИ Сигеру (JP) |
分类号 |
A61K47/38;A61K9/22;A61K9/28;A61K31/4439;A61K47/04;A61K47/10;A61K47/14;A61K47/32;A61K47/44;A61P1/04 |
主分类号 |
A61K47/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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