PYRROLOPYRIMIDINETHIONE DERIVATIVE

摘要

A compound represented by the following formula, which has inhibitory activity against GSK-3. (I) In the formula, A<1> and A<3> each is a single bond or an aliphatic hydrocarbon; A<2> and A<4> each is a single bond, CO, COO, etc.; G<1> is a single bond, alicyclic hydrocarbon, aromatic hydrocarbon, etc.; G<2> is hydrogen, an aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, etc.; A<5> is a single bond or NR; R<2> is hydrogen, halogeno, an aliphatic hydrocarbon, etc.; A<6> is a single bond, NR, CO, etc.; and R<3> is hydrogen, halogeno, nitro, a saturated aliphatic hydrocarbon, etc.; provided that R is hydrogen or a lower aliphatic hydrocarbon group.