发明名称 Heterocyclic compounds useful as inhibitors of tyrosine kinases
摘要 Disclosed are novel compounds of formula (I):wherein Ar1, X, Y, P, Q and Het are defined herein, which are useful as inhibitors of certain protein tyrosine kinases and are thus useful for treating diseases resulting from inappropriate cell proliferation, which include autoimmune diseases, chronic inflammatory diseases, allergic diseases, transplant rejection and cancer, as well as conditions resulting from cerebral ischemia, such as stroke. Also disclosed are pharmaceutical compositions comprising these compounds, processes for preparing these compounds and novel intermediate compounds useful in these processes.
申请公布号 US6844435(B2) 申请公布日期 2005.01.18
申请号 US20020271222 申请日期 2002.10.15
申请人 BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. 发明人 SNOW ROGER JOHN;GAO DONGHONG A.;GOLDBERG DANIEL R.;HAMMACH ABDELHAKIM;KUZMICH DANIEL;MORWICK TINA MARIE;MOSS NEIL;PROKOPOWICZ, III ANTHONY S.;SELLIAH ROBERT D.;TAKAHASHI HIDENORI
分类号 A61K31/517;A61P1/04;A61P3/10;A61P9/00;A61P9/10;A61P11/06;A61P17/06;A61P19/02;A61P19/08;A61P25/00;A61P35/00;A61P37/02;A61P37/06;A61P43/00;C07D487/04;(IPC1-7):C07D487/04;C07D235/14 主分类号 A61K31/517
代理机构 代理人
主权项
地址