发明名称 NEW BETA-CRYSTALLINE FORM OF PERINDOPRIL TERT-BUTYLAMINE SALT AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME
摘要 <P>PROBLEM TO BE SOLVED: To provide a new beta-crystal form of perindopril tert-butylamine salt. <P>SOLUTION: The method for production of a beta-crystal form of the compound expressed by formula 1, comprises collecting solid obtained by heating at refluxing a solution of the perindopril tert-butylamine salt in dichloromethane, rapidly cooling to 0&deg;C and then filtering product solid, or heating at refluxing the perindopril ter-butylamine salt solution of ethyl acetate, rapidly cooling to 5&deg;C and then filtering the product solid. <P>COPYRIGHT: (C)2005,JPO&NCIPI
申请公布号 JP2005002121(A) 申请公布日期 2005.01.06
申请号 JP20040206159 申请日期 2004.07.13
申请人 LAB SERVIER 发明人 PFEIFFER BRUNO;GINOT YVES-MICHEL;COQUEREL GERARD;BEILLES STEPHANE
分类号 A61K9/20;A61K31/404;A61K38/00;A61K38/55;A61K45/00;A61P7/10;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P13/02;A61P43/00;B01D9/02;C07D209/42;C07K1/30;C07K5/062 主分类号 A61K9/20
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