发明名称 |
METHOD FOR GENERATING PRIMATE TROPHOBLASTS |
摘要 |
<p>The first method to cause a culture of human and other primate stem cells to directly and uniformly differentiate into a committed cell lineage is disclosed. Treatment of primate stem cells with a single protein trophoblast induction factor causes the cells to transform into human trophoblast cells, the precursor cells of the placenta. Several protein factors including bone morphogenic protein 4 (BMP4), BMP2, BMP7, and growth and differentiation factor 5 can serve as trophoblast-inducting factors.</p> |
申请公布号 |
EP1490506(A2) |
申请公布日期 |
2004.12.29 |
申请号 |
EP20030744695 |
申请日期 |
2003.03.14 |
申请人 |
WICELL RESEARCH INSTITUTE, INC. |
发明人 |
XU, REN-HE;THOMSON, JAMES, A. |
分类号 |
C12Q1/02;A61K38/18;C12N5/02;C12N5/073;C12N5/10;(IPC1-7):C12Q1/02;C12N5/08;C12N5/06 |
主分类号 |
C12Q1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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