NANO AND MICROPARTICLE DRUG DELIVERY SYSTEMS COMPRISING POLYESTERS CONTAINING ALIPHATIC DICARBOXYLATE RESIDUES AND RESIDUES OF ALIPHATIC POLYOLS

摘要

A nano or microparticle drug delivery system comprising a pharmaceutically-active agent and nano or microparticles of a linear aliphatic polyester, the polyester having a polymer backbone containing aliphatic dicarboxylate residues and residues of an aliphatic polyol wherein the polymer backbone includes at least one aliphatic polyol residue containing a moiety capable of interacting with the pharmaceutically-active agent. The nano or microparticle drug delivery system can be used to deliver a pharmaceutically-active agent to an animal, including human.