| 发明名称 |
INHIBITORS OF FARNESYL PROTEIN TRANSFERASE |
| 摘要 |
DISCLOSED ARE QUINOLINE AND BENZAZEPINE DERIVATIVES THAT INHIBIT FARNESYL-PROTEIN TRANSFERASE (FTASE) AND THE FARNESYLATION OF THE ONCOGENIC PROTEIN RAS. THUS, THE COMPOUNDS ARE USEFUL AS ANTI-CANCER AGENTS. THE COMPOUNDS ARE ALSO USEFUL IN THE TREATMENT OF DISEASES OTHER THAN CANCER.
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| 申请公布号 |
MY117961(A) |
申请公布日期 |
2004.08.30 |
| 申请号 |
MYPI9802919 |
申请日期 |
1998.06.26 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
RAJEEV S. BHIDE;CHARLES Z. DING;JOHN T. HUNT;SOONG-HOON KIM;KATERINA LEFTHERIS |
| 分类号 |
C07D233/02;C07D403/08;A61K31/33;A61K31/395;A61K31/44;A61K31/4709;A61K31/54;A61K31/55;A61P35/00;A61P37/02;A61P43/00;C07D233/04;C07D233/54;C07D401/06;C07D401/14;C07D403/02;C07D403/06;C07D403/12;C07D403/14;C07D409/14 |
主分类号 |
C07D233/02 |
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