BETA-2-GLYCOPROTEIN 1 IS AN INHIBITOR OF ANGIOGENESIS

摘要

The present disclosure provides a method of inhibiting angiogenesis within a tissue of interest by providing either intact or nicked beta2-Glycoprotein 1(beta2GP1) to cells associated with the tissue. The presence of beta2GP1 inhibits angiogenesis within the tissue, in part by preventing neovascularization into the tissue. The disclosure also provides a method for treating tumors by providing beta2GP1 to the tumor.