| 发明名称 |
PROCESS FOR PREPARING OXAZOLINES FROM TETRAHYDROFURANS |
| 摘要 |
<p>Methods for the preparation of chemical intermediates in the synthesis of HIV-protease inhibitors related to and including nelfinavir mesylate are disclosed. The method of this invention comprises converting tetrohydran derivatives into oxazolines to provide key reaction intermediates for the preparation of nelfinavir. Also disclosed is a method for the preparation of a chiral amino alcohol from an epoxy-tetrahydrofuran.</p> |
| 申请公布号 |
SI1224177(T1) |
申请公布日期 |
2004.06.30 |
| 申请号 |
SI20000030333T |
申请日期 |
2000.10.19 |
| 申请人 |
AGOURON PHARMACEUTICALS, INC. |
发明人 |
BUSSE JULIETTE KHARSA;ZOOK SCOTT EDWARD;BORER BENNETT CHAPLIN |
| 分类号 |
C07D217/26;A61K31/472;A61P31/18;A61P43/00;C07B61/00;C07D263/14;C07D307/22;C07D413/06;(IPC1-7):C07D263/14 |
主分类号 |
C07D217/26 |
| 代理机构 |
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