发明名称 |
WATER-SOLUBLE ANIONIC BACTERIOCHLOROPHYLL DERIVATIVES AND THEIR USES |
摘要 |
The invention provides anionic water-soluble tetracyclic and pentacyclic bacteriochlorophyll derivatives (Bchls) containing at least one, preferably two or three, negatively charged groups and/or acidic groups that are converted to negatively charged groups at the physiological pH, preferably Bchls having a group COO<->, COS<->, SO3<->, PO3<2->, COOH, COSH, SO3H, and/or PO3H2 bound through an ester or amide bond to one or more of the positions 17<3>, 13<3>, and 3<2> of the tetracyclic or pentacyclic Bchl molecule, for photodynamic therapy and diagnosis. |
申请公布号 |
WO2004045492(A2) |
申请公布日期 |
2004.06.03 |
申请号 |
WO2003IL00973 |
申请日期 |
2003.11.17 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT CO. LTD.;SCHERZ, AVIGDOR;BRANDIS, ALEXANDER;MAZOR, OHAD;SALOMON, YORAM;SCHEER, HUGO |
发明人 |
SCHERZ, AVIGDOR;BRANDIS, ALEXANDER;MAZOR, OHAD;SALOMON, YORAM;SCHEER, HUGO |
分类号 |
A61K31/40 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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