发明名称 POLYMORPHIC FORMS OF 1-4-(5-CYANOINDOL-3-YL) BUTYL-4-(2-CARBAMOYLBENZOFURAN-5-YL) PIPERAZINE HYDROCHLORIDE
摘要 The invention relates to new crystalline modifications of the hydrochloride of 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine, crystalline modification of the dihydrochloride of 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine and amorphous 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine hydrochloride which are suitable in particular for the preparation of solid medicaments for the treatment or prevention of depressive disorders, anxiety disorders, bipolar disorders, mania, dementia, substance-related disorders, sexual dysfunctions, eating disorders, obesity, fibromyalgia, sleeping disorders, psychiatric disorders, cerebral infarct, tension, for the therapy of side-effects in the treatment of hypogonadism, secondary amenorrhea, premenstrual syndrome and undesired puerperal lactation.
申请公布号 IL159426(D0) 申请公布日期 2004.06.01
申请号 IL20020159426 申请日期 2002.06.05
申请人 MERCK PATENT GMBH 发明人
分类号 C07D405/00;A61K31/496;A61P1/14;A61P3/04;A61P9/10;A61P9/12;A61P15/00;A61P15/10;A61P21/00;A61P25/04;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P29/02;C07D405/12;(IPC1-7):C07D 主分类号 C07D405/00
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